CPRD – Probably the most utilized data-set in Europe for Real World Evidence studies?
27 Sep 2019

More than 2300 scientific publications have been generated from the CPRD database. This would probably make it the most utilized data-set for RWE research. 


As of September 2019, 1600+ GP practices in the UK have contributed data, which included 35 million patients, of whom over 11 million are currently registered at contributing practices. Click here to find all the publications. 


If you are interested to learn more about this data-set, don’t miss our upcoming webinar (sign-up here).

In the recent publication “Data resource profile: Clinical Practice Research Datalink (CPRD) Aurum” by A Wolf et al, they give a good summary of the data set:

  • CPRD Aurum is a UK primary care database set up for public health research and benefit, updated monthly for observational research, with standard linkages to hospital, mortality, cancer, mental health and deprivation data.
  • De-identified coded primary care data are collected from GP practices that have consented to provide data to CPRD Aurum.
  • Symptoms, diagnoses, prescriptions, immunizations, tests and lifestyle factors are recorded by the GP or other practice staff, and CPRD Aurum has been linked to additional secondary care databases.
  • Access to data for public health research is subject to data governance requirements and contractual obligations being met.


Wolf, Achim, Daniel Dedman, Jennifer Campbell, Helen Booth, Darren Lunn, Jennifer Chapman, and Puja Myles. ‘Data Resource Profile: Clinical Practice Research Datalink (CPRD) Aurum’. International Journal of Epidemiology. Accessed 26 September 2019. https://doi.org/10.1093/ije/dyz034.