Correlation between midlife cardiovascular fitness and development of dementia, demonstrating how important Real World Evidence is to answer important question.
08 Mar 2019

Last week I read an interesting study that evaluated the impact of greater cardiovascular fitness in midlife is associated with decreased dementia risk in women. The study shows a stunning decrease in the risk of dementia. It was critiqued by some, but after considering the critique it is still a 60% reduction in the risk of dementia.

This is a good example to demonstrate the value of Real World Evidence is to answer important questions. Could it be that exercise should be one potential treatment modality for patients with pre-disposition for dementia / Alzheimer?

Should the cardiovascular fitness be a variable that is considered in future studies about the effect of new Alzheimer drugs?

I believe that high quality Real World Evidence with the right scope of data provides a disruption in how we can analyse many important questions.

Time to go for a run…

https://n.neurology.org/content/90/15/e1298.long

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