Knowledge base
Archived articles from Synergus RWE, kept for reference.
13 articles
Germany is introducing 20 % performance-based pricing on digital health
Several changes are ongoing regarding the German DIGA process for Digital Health solutions. One of the more interesting aspects is the introduction of a performance-based payment for at least 20% of the total…
Real-World data provide essential insights about Myeloma
Characteristics of patients outside typical RCTs: “The overall incidence and median age were both higher than in most previous studies, indicating a more complete coverage of older patients. Myeloma survival in Sweden…
Swedish drug registry – Data since 2005 and perfect linkage to other datasets
Sweden established the Prescribed drug registry was established July 2005, covering the whole Swedish population. (1) Through the personal identity number(2) it can be seamlessly linked to other data sets: The more than…
High quality RWE - Registry based randomized clinical trials
There is an increasing need to develop high-quality evidence to support decision makers. There are many important improvements that require such big trials that they are never done. In the recent decade there has been a…
High-quality RWE – Transparency about data quality
The foundation for high-quality RWE is the ability to define the right variables, the ability to collect and finally the ability to transparently report the quality of the data. The ability to succeed with this very…
The best real-world data setting for diabetes research – How much data is required?
The Swedish setting provides an extremely rich data set with very high quality for diabetes research. The foundation is the national diabetes registry (NDR) that covers 92,7% of all patients in the country diagnosed…
Can RWE contribute to investigate and contain the current outbreak of novel coronavirus?
Early this month, Chines National Medical Products Administration published guideline 1 for applying real-world evidence (RWE) to support drug development as the No.1 announcement of this year. According to this…
Transferring Outcomes Data for National Decision Making: The Illusion of Simplicity What is the HTA perspective on transferability?
This is a blog in our series about the issues relating to the transferability of outcomes for national decision making. Click on this link to get the other posts related to this topic. In this blog post we will provide…
Transferring Outcomes Data for National Decision Making: The Illusion of Simplicity
Variation in outcomes and health care delivery Breast Cancer – Part 2 In this blog-post series we are analysing different aspects about transferability of outcomes, either from RCT to Real-World setting or between…
Transferring Outcomes Data for National Decision Making: The Illusion of Simplicity - Understanding why healthcare delivery is a significant issue
This blog is part of our series on the issues related to the transferability of outcomes, for National decision making. You can follow this link to read our other posts within this topic. To illustrate the impact and…
Transferring Outcomes Data: The Illusion of Simplicity
As previously announced , we have started a project that will look at issues relating to “Methodological aspects of evaluating transferability of Real World Evidence results between countries / settings”. As part of…
Combination of app-based data collection linked to rich data-sets provides a unique (largely untapped) gold mine
Many have heard that the Nordic Countries have good opportunities for real world evidence studies. From the activity we can observe, it appears that the opportunity is not fully understood by industry. There is a large…
Correlation between midlife cardiovascular fitness and development of dementia, demonstrating how important Real World Evidence is to answer important question.
Last week I read an interesting study that evaluated the impact of greater cardiovascular fitness in midlife is associated with decreased dementia risk in women. The study shows a stunning decrease in the risk of…